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IONS

Ionis Pharmaceuticals, Inc.

Stock

$43.54−0.46 (−1.05%)Close Oct 2, 2026

May 17, 1991 – Oct 2, 2026, Dividends reinvested

Final balance
$43,540
CAGR
+4.25%
Max drawdown
−91.72%
Sharpe ratio
0.38

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Growth of $10,000

Trailing returns

Annualized from 3Y
1M
−29.01%
3M
−46.77%
6M
−41.78%
YTD
−44.96%
1Y
−36.35%
3Y
+0.08%
5Y
+5.34%
10Y
+1.74%
15Y
+13.20%
20Y
+9.39%
25Y
+3.56%
30Y
+3.16%
Since 1991
+4.25%

Metrics

Since 1991
Volatility61.84%
Sortino ratio0.57
Calmar ratio0.05
Best year, 2013+281.61%
Worst year, 2002−70.30%
Positive years17 of 34
Longest drawdown13.5 years

Worst drawdowns

Since 1991
DeclinePeakBottomRecoveredLength
−91.7%Mar 2000Mar 2003Sep 201313.5 years
−84.1%Nov 1991Nov 1994Jun 19964.6 years
−78.7%Jun 1996Dec 1999Mar 20003.7 years
−73.2%Mar 2015Jun 2016Mar 20194 years
−70.4%Apr 2019Apr 2025Feb 20266.8 years

Annual returns

1991 from May 17 · 2026 through Oct 2